In a skillet over medium heat, melt 1 tablespoon of butter. Add the sliced beef, Worcestershire sauce, garlic powder, onion powder, salt, and pepper. Cook until the beef is browned and cooked through, about 5-7 minutes.

Remove the beef from the skillet and set aside. In the same skillet, add another tablespoon of butter. Place two slices of bread in the skillet.

Top each slice of bread with equal portions of the cooked beef and a slice of cheddar cheese.

Cover with the remaining slices of bread and grill until golden brown and the cheese is melted, about 3-4 minutes per side.

Remove the sandwiches from the skillet, slice in half, and serve hot.