Preheat the oven to 375 degrees F and line a baking sheet with parchment paper. Lightly flour the parchment paper.

In a large bowl, add flour, onion powder, garlic powder, baking powder, and salt. Whisk together until combined.

In a medium bowl, add cottage cheese, cheddar cheese, eggs, ham, and chives. Mix until fully combined.

Add the cottage cheese mixture to the large bowl with dry ingredients and mix with a wooden spoon or silicone spatula. When the dough begins to form, switch to using clean floured hands to mix the dough and form a large dough ball. Add a sprinkle of flour if the dough is too sticky; it will be slightly sticky but should form into a ball.

Place the dough ball on the lined baking sheet and flatten with your hands to form a rectangle, roughly 7” by 10”.

Using a knife or bench scraper, divide the dough into 12 equal biscuits. Space the biscuits apart evenly on the baking sheet.

Bake biscuits for 22-25 minutes until tops are slightly golden brown and bottoms are golden brown. Allow to cool slightly before serving.